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Symbol
Name
ID
Syk
spleen tyrosine kinase
MGI:99515
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal osteoclast differentiation
increased B cell proliferation
impaired neutrophil phagocytosis
abnormal B cell differentiation
decreased late pro-B cell number
arrested B cell differentiation
abnormal NK cell differentiation
increased neutrophil cell number
decreased B cell number
absent pre-B cells
abnormal T cell number
abnormal B cell morphology
abnormal neutrophil physiology
impaired granulocyte bactericidal activity
abnormal platelet physiology
Availability Mouse Genotype
Sykm1Btlr/Sykm1Btlr
SykM2Btlr/SykM2Btlr
Syktm1.1Tara/Syktm1.1Tara
Syktm1Paw/Syktm1Paw
Syktm1Tyb/Syktm1Tyb
SykM2Btlr/Syk+
Syktm1.1Nns/Syktm1.1Nns
Tg(Pf4-icre)Q3Rsko/0  (conditional)
Syktm1.2Tara/Syktm1.2Tara
Tg(Cr2-cre)3Cgn/0  (conditional)
Syktm1Tyb/Syktm1.2Tara
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Syktm1Tyb/Syktm1.2Tara
Tg(S100A8-cre,-EGFP)1Ilw/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory